【多选题】What will adipocytes do when the demand for fuel rises?
A.
When the demand for fuel rises (between meals, for example), lipases in adipocytes hydrolyze stored triacylglycerols (TAGs) to release free fatty acids, which can travel in the bloodstream to skeletal muscle and the heart.
B.
T he release of fatty acids from adipocytes is greatly accelerated by epinephrine, which stimulates the cAMP-dependent phosphorylation of perilipin and thus gives lipases specific for tri-, di-, and monoacylglycerols access to TAGs in lipid droplets .
C.
Hormone-sensitive lipase is also stimulated by phosphorylation, but this is not the main cause of increased lipolysis.
D.
Insulin counterbalances this effect of epinephrine, decreasing the activity of the lipase.