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What is the physiological role of retinoid hormones ?A.
The retinoid hormones are potent hormones that regulate the growth, survival, and differentiation of cells via nuclear retinoid receptors. The prohormone retinol is synthesized from β-carotene, primarily in liver, and many tissues convert retinol to the hormone retinoic acid (RA).
B.
RA binds its specific receptor (RAR) in the nucleus, forms a dimer with another nuclear protein, retinoid X receptor (RXR), and alters the rate of expression of genes responsive to R
C.
All tissues are retinoid targets, as all cell types have at least one form of nuclear retinoid receptor. In adults, the most significant targets include cornea, skin, epithelia of the lungs and trachea, and the immune system, all of which undergo constant replacement of cells.
D.
RA regulates the synthesis of proteins essential for growth or differentiation. Excessive vitamin A (the precursor to retinoid hormones) can cause birth defects, and pregnant women are advised not to use the retinoid creams that have been developed for treatment of severe acne.
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举一反三
【单选题】大鱼际肌的支配神经为（ ）
A.
均为尺神经支配
B.
均为正中神经支配
C.
除拇收肌为尺神经支配外，其余为正中神经支配
D.
除拇收肌为正中神经支配外均为尺神经支配
E.
内侧为尺神经支配，外侧为正中神经支配
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