【多选题】When integrating ethics into neurological research, the key ethical issues are:
A.
How might a clinician best determine a patient's competence for understanding the risks and benefits before deciding to participate in research? How can a patient consent to participate in research if the disease affects the very organ that grants consent?
B.
Once a patient is involved in a research study, what are best practices for managing unexpected physical or perceived nonphysical harm?
C.
Who should control devices that affect mood and the brain’s reward systems? The patient? The doctor?
D.
If a device is placed in the brain as part of a research study, what is a researcher's responsibility for continued care of the patient and upkeep of the device? Who owns the data collected by such devices?