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【多选题】
有关注射剂灭菌的叙述错误的是A.
灌封后的注射剂必须在12h内进行灭菌
B.
注射剂在121.5℃需30min才能杀死细胞和芽孢
C.
微生物在中性溶液中耐热性最大，碱性溶液中次之，酸性不利于微生物的发育
D.
能达到灭菌的前提下，可适当降低灭菌温度和缩短灭菌时间
E.
滤过灭菌是注射剂生产中最常用的灭菌方法
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