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【多选题】
列关于抗胆碱能药物在治疗COPD中作用的描述，哪些是正确的（）。A.
M1受体位于副交感神经节，阻断这些受体可以缓解支气管痉挛作用
B.
M2受体能抑制乙酰胆碱的释放，阻断M2受体可增加乙酰胆碱释放，使支气管扩张效应减弱
C.
M1／M3选择性拮抗剂为新的支气管扩张剂，用于COPD治疗，并不增加乙酰胆碱释放
D.
非选择性的抗胆碱能制剂同时阻断M1和M2受体
E.
应用选择性的毒蕈碱拮抗剂比非选择性的药物（托溴铵）更有优越性
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