With the outbreak of the economic crunch, many small- and medium-sized enterprises ran out financial troubles and some have even applied for bankruptcy.
B.
With the crisis , many small- and medium-sized enterprises ran into financial troubles and some have even bankrupted.
C.
With the outbreak of the economic crunch, many small- and medium-sized enterprises ran into financial troubles and some have even applied for bankruptcy.
D.
Because of the start of the financial crisis, many small- and medium-size enterprises have gotten into financial difficulties.