What is the structure of the SMC proteins (structural maintenance of chromosomes)?
A.
The primary structure of SMC proteins consists of five distinct domains.
B.
The amino- and carboxyl-terminal globular domains, N and C, each of which contains part of an ATP-hydrolytic site, are connected by two regions of α-helical coiled-coil motifs joined by a hinge domain.
C.
The proteins are generally dimeric, forming a V-shaped complex that is thought to be tied together through the protein’s hinge domains.
D.
One N and one C domain come together to form a complete ATP-hydrolytic site at each free end of the V.