【多选题】Recommendations of the European Society of Human Reproduction and Embryology (ESHRE) and the European Society of Human Genetics (ESHG) on human germline gene editing are:
A.
After consulting its membership and experts, this final version of the Recommendations was endorsed by the Executive Committee and the Board of the respective Societies in May 2017. Taking account of ethical arguments, we argue that both basic and pre-clinical research regarding GLGE can be justified, with conditions.
B.
Furthermore, while clinical GLGE would be totally premature, it might become a responsible intervention in the future, but only after adequate pre-clinical research.
C.
Safety of the child & future generations is a major concern. Future discussions must also address priorities among reproductive and potential non-reproductive alternatives, such as PGD and somatic editing, if that would be safe and successful.
D.
The prohibition of human germline modification, however, needs renewed discussion among relevant stakeholders, including the general public and legislators.