In order for a cell to carry out its biologic functions, the intracellular reactions need to be directed to follow a certain pathway. Which one statement best describes the direction a chemical reaction will follow?
A.
A reaction with positive free energy will proceed in the forward direction if the substrate concentration is raised high enough.
B.
Under standard conditions, a reaction will proceed in the forward direction if the free energy Δ G0 ′ is positive.
C.
The direction of a reaction is independent of the initial substrate and product concentrations because the direction is determined by the change in free energy.
D.
The concentration of all of the substrates must be higher than that of all of the products for the reaction to proceed in the forward direction.
E.
The enzyme for the reaction must be working at >50% of its maximum efficiency for the reaction to proceed in the forward direction.