【多选题】Which of the following statements about the synthesis of yeast genome are correct?
A.
In 2009, the first synthetic yeast genome project (Sc. 2.0 project) was launched to redesign and chemically synthesize the entire Saccharomyces cerevisiae genome.
B.
In 2011, the right arm of chromosome 9 & the left arm of chromosome 6 were successfully chemically synthesized.
C.
In 2017, five redesigned yeast chromosomes were completed; this accomplishment represents over one-third of the Sc. 2.0 project. During this project, scientists gradually established basic principles and methodologies for the design and synthesis of yeast artificial chromosomes.
D.
BioStudio, a software for design and reprogramming of a complete genome on computers, has also been published. Recently, 16 natural chromosomes of S. cerevisiae were successfully fused into a single chromosome, similar to that found in prokaryotic cells; the artificial S. cerevisiae still has normal cellular functions.