【单选题】A 47-year-old woman has had worsening dyspnea for the past 5 years. A chest CT scan shows panlobular emphysema. Laboratory studies show the PiZZ genotype of αl-antitrypsin deficiency. A liver biopsy s...
A.
Excessive hepatic synthesis of αl -antitrypsin
B.
Retention in the endoplasmic reticulum because of poorly folded αl -antitrypsin
C.
Decreased catabolism of αl -antitrypsin in lysosomes
D.
Inability to metabolize αl -antitrypsin
E.
Impaired dissociation of αl -antitrypsin from chaperones
【简答题】The performance was posted on line and before long, the 47-year-old Scottish woman has been famous all over the world. Speaking from her home in Scotland, Ms Boyle said that she hasn’t thought of chan...
【单选题】A 47-year-old woman with a history of rheumatic fever is examined by her physician. Physical examination is significant for a low-pitched, rumbling, diastolic murmur preceded by an opening snap. The a...