Which of the following is true about the holoenzyme in an open complex?
A.
The DNA is bound mainly to the sigma-subunit.
B.
There no interaction between the sigma factor and the -10 region.
C.
There are two Na+ ions in the core enzyme .
D.
Region 2.4 of the sigma-factor binds to the -35 region.
E.
The DNA is bound mainly to the sigma-subunit and there no interaction between the sigma factor and the -10 region are both true.